Stewardship of Proton Pump Inhibitors: Considerations for Use and Deprescribing
Activity Description:
Long-term use of proton pump inhibitors (PPIs) without an ongoing indication or evidence of benefit contributes to increased pill burden, increased medication-related costs, and potential adverse effects. This written article reviews FDA-approved labeling for PPIs, summarizes treatment guidelines regarding appropriate dosage and duration of treatment, and is designed to help learners identify appropriate indications for long-term use of PPIs. In the absence of an indication for long-term use, recommendations are provided to assist with developing patient-specific plans to deprescribe PPIs and manage symptoms.
Activity Type: Knowledge-based, online home-study
Learning Objectives:
- Identify the appropriate dosing and duration of PPIs based on FDA-approved indications and guideline recommendations.
- Discuss considerations for long-term PPI therapy.
- Determine when deprescribing of PPIs is appropriate based on patient-specific factors.
Target Audience: Physicians, physician assistants, nurse practitioners, pharmacists, and other healthcare providers.
Initial Release Date: 8/14/2023
Expiration Date: 8/13/2026
Cost and Registration: There is no fee for this activity. The program is supported by the New York State Department of Health Medicaid Prescriber Education Program (MPEP).
Activity Components for Continuing Education Credit: To obtain continuing education credit, complete the required materials. This continuing education activity contains a pre-test, written article, post-test, and program evaluation. Credit will be awarded upon successful completion of the post-test activity, with a score of 70% or greater.
For physicians/providers:
Accreditation: The University at Buffalo Jacobs School of Medicine and Biomedical Sciences is accredited by the ACCME to provide continuing medical education for physicians.
Certification: The University at Buffalo Jacobs School of Medicine and Biomedical Sciences designates this Internet Enduring Activity for a maximum of 1.0 AMA PRA Category 1 Credit (TM). Physicians should claim only the credit commensurate with the extent of their participation in the activity.

For pharmacists:
The University at Buffalo School of Pharmacy and Pharmaceutical Sciences is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. This knowledge-based activity has been assigned ACPE# 0044-0000-23-033-H01-P and will award 1.0 contact hour (0.10 CEU) of continuing pharmacy education credit. Credit will be uploaded to the CPE Monitor for those who complete all components of this activity.
Questions? Please email: pharmacyce@buffalo.edu
The following planners, presenters and others have either indicated financial relationships with ineligible companies or that no financial relationships exist. An ineligible company is any entity whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. ACCME Standards for Integrity and Independence in Accredited Continuing Education
The following planners/presenters/others do not have any relevant financial relationships with ineligible companies: | |
Role in Activity | Name |
Reviewer, Author | Brenda Basile, PharmD, MS |
Reviewer, Planner | Edward M. Bednarczyk, PharmD |
Reviewer, Author | Holly V. Coe, PharmD |
Planner | Marsha Nelson |
Reviewer | Barbara Rogler, PharmD, MS |
Activity Director, Reviewer | Alexia Sroka, PharmD, BCPS |
No commercial support was received for this activity.
- Chrome, version 133 (64-bit) or higher
- Firefox, version 135 (64-bit) or higher
- Safari, version 18 (64-bit) or higher
- Edge, version 133 (64-bit) or higher
- Internet Explorer is NOT supported
- Smartphones have limited support. Use a desktop or laptop computer for the best experience.
- Chrome, version 133 (64-bit) or higher
- Safari, version 18 (64-bit) or higher
- Internet Speed: 5 Mbps
- Processor: Dual-core 2Ghz or higher
- Memory (RAM): 4GB
- Storage: Storage requirements are minimal unless materials are downloaded.
For questions about this activity, please contact: pep@nysdoh.suny.edu